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Authors Mutimer J, Gillespie G, Lovering AM, Porteous AJ |
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Institute Trauma and Orthopaedics, Southmead Hospital, Bristol, United Kingdom. |
Review of experimental research results
REVIEW OF THE EXPERIMENTAL STUDIES RESULTS
Key words: total hip arthroplasty, total knee arthroplasty, antibiotic-loaded bone cement, periprosthetic joint infection
Introduction
Total hip and total knee arthroplasty (THA, TKA) are clinically efficacious and cost-effective interventions with numerous investigators reporting excellent long-term results in terms of reducing pain and improving function and quality of life in patients with debilitating hip and knee disease (Bozic et al., 2009-2010).
Along with a steady rise in the volume of joint prostheses implanted every year worldwide, there has been a rise in revision THA and TKA (OECD, 2014). Among the main reason for THA revision, infection accounts for 12 - 14.8% (NJR 2013; Bozic et al., 2009), while for the TKA the percentage is much higher, 22 - 25.2% (NJR 2013; Bozic et al., 2010). Periprosthetic joint infection (PJI) is therefore among the main reason for revision.
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По данным современной литературы, сегодня в медицинской практике достаточно широко используют костные цементы, в которые доктора самостоятельно добавляют антибиотик, для первичного и ревизионного эндопротезирования и даже для изготовления спейсеров (временных цементных имплантатов) в условиях операционной.
E. Meani · C. Roman`o · L. Crosby · G. Hofmann (Eds.)
Editorial Coordinator: G. Caloneg
With 173 Figures in 317 Parts and 49 Tables
An In Vitro Comparison of Antimicrobial Efficacy
Matthew W. Squire, MD,*yBrian J. Ludwig, MD,*yJonathan R. Thompson, BS,z
Jason Jagodzinski, BS,zDerek Hall, BS,zand David Andes, MD§∥
Jill Meyer, PhD, Geoff Piller, MS, Carol A. Spiegel, PhD, Scott Hetzel, MS, and Matthew Squire, MD, MS
Investigation performed at the University of Wisconsin Hospitals and Clinics, Madison, Wisconsin
